6OBJ

Structure of a DNA-bound dimer extracted from filamentous SgrAI endonuclease in its activated form

Summary for 6OBJ

Entry DOI	10.2210/pdb6obj/pdb
EMDB information	20015
Descriptor	SgraIR restriction enzyme, DNA (26-MER), MAGNESIUM ION (3 entities in total)
Functional Keywords	restriction endonuclease, dnase, allostery, bacterial innate immunity, filament, hyper-activation, substrate specificity, hydrolase-dna complex, hydrolase/dna
Biological source	Streptomyces griseus More
Total number of polymer chains	4
Total formula weight	100824.59
Authors	Polley, S.,Lyumkis, D.,Horton, N.C. (deposition date: 2019-03-20, release date: 2020-02-26, Last modification date: 2024-03-20)
Primary citation	Polley, S.,Lyumkis, D.,Horton, N.C. Mechanism of Filamentation-Induced Allosteric Activation of the SgrAI Endonuclease. Structure, 27:1497-1507.e3, 2019 Cited by PubMed: 31447289 DOI: 10.1016/j.str.2019.08.001 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation