6O9E

Structure of HIV-1 Reverse Transcriptase in complex with DNA and INDOPY-1

Summary for 6O9E

Entry DOI	10.2210/pdb6o9e/pdb
Related PRD ID	PRD_900003
Descriptor	Reverse transcriptase p66, TETRAETHYLENE GLYCOL, Reverse transcriptase p51, ... (11 entities in total)
Functional Keywords	human immunodeficiency virus 1, protein/dna, nucleotide-competing reverse transcriptase inhibitor, transferase, transferase-dna complex, transferase/dna
Biological source	Human immunodeficiency virus type 1 (HIV-1) More
Total number of polymer chains	6
Total formula weight	254104.87
Authors	Ruiz, F.X.,Hoang, A.,Das, K.,Arnold, E. (deposition date: 2019-03-13, release date: 2019-10-23, Last modification date: 2023-10-11)
Primary citation	Ruiz, F.X.,Hoang, A.,Das, K.,Arnold, E. Structural Basis of HIV-1 Inhibition by Nucleotide-Competing Reverse Transcriptase Inhibitor INDOPY-1. J.Med.Chem., 62:9996-10002, 2019 Cited by PubMed: 31603676 DOI: 10.1021/acs.jmedchem.9b01289 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation