Horse liver L57F alcohol dehydrogenase complexed with NAD and pentafluorobenzyl alcohol

Summary for 6O91

Related4DWV 5KCP
DescriptorAlcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywordsalcohol dehydrogenase, nad, pentafluorobenzyl alcohol, leu57 to phe57 substitution, horse liver e enzyme, oxidoreductase
Biological sourceEquus caballus (Horse)
Total number of polymer chains2
Total molecular weight82350.11
Plapp, B.V. (deposition date: 2019-03-12, release date: 2019-04-10)
Primary citation
Plapp, B.V.,Kim, K.
Substitutions of amino acid residues in the substrate binding site of horse liver alcohol dehydrogenase have small effects on structure but significantly affect catalysis of hydrogen transfer.
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.133100 0.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution