6O6N
Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA
Summary for 6O6N
Entry DOI | 10.2210/pdb6o6n/pdb |
Descriptor | TetR family transcriptional regulator, Arachinoyl-CoA, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | tetr-like transcription factor, fatty acid biosynthesis regulation, transcription |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 1 |
Total formula weight | 22725.32 |
Authors | Larrieux, N.,Trajtenberg, F.,Lara, J.,Gramajo, H.,Buschiazzo, A. (deposition date: 2019-03-07, release date: 2020-03-11, Last modification date: 2024-03-13) |
Primary citation | Lara, J.,Diacovich, L.,Trajtenberg, F.,Larrieux, N.,Malchiodi, E.L.,Fernandez, M.M.,Gago, G.,Gramajo, H.,Buschiazzo, A. Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11:3703-3703, 2020 Cited by PubMed: 32710080DOI: 10.1038/s41467-020-17504-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report