6O6N

Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA

6O6N の概要

• エントリーDOI: 10.2210/pdb6o6n/pdb
• 分子名称: TetR family transcriptional regulator, Arachinoyl-CoA, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: tetr-like transcription factor, fatty acid biosynthesis regulation, transcription
• 由来する生物種: Mycobacterium tuberculosis
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 22725.32

構造登録者

Larrieux, N.,Trajtenberg, F.,Lara, J.,Gramajo, H.,Buschiazzo, A. (登録日: 2019-03-07, 公開日: 2020-03-11, 最終更新日: 2024-03-13)

• 主引用文献: Lara, J.,Diacovich, L.,Trajtenberg, F.,Larrieux, N.,Malchiodi, E.L.,Fernandez, M.M.,Gago, G.,Gramajo, H.,Buschiazzo, A.; Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.; Nat Commun, 11:3703-3703, 2020; PubMed: 32710080; DOI: 10.1038/s41467-020-17504-x

実験手法

X-RAY DIFFRACTION (1.7 Å)