6O6A
Structure of the TRPM8 cold receptor by single particle electron cryo-microscopy, ligand-free state
Summary for 6O6A
| Entry DOI | 10.2210/pdb6o6a/pdb |
| Related | 6O6R 6O72 6O77 |
| EMDB information | 0631 0636 0638 0639 |
| Descriptor | Transient receptor potential cation channel subfamily M member 8, CHOLESTEROL HEMISUCCINATE, SODIUM ION (3 entities in total) |
| Functional Keywords | transport protein, ion channel, trpm8 |
| Biological source | Parus major (great tit) |
| Total number of polymer chains | 4 |
| Total formula weight | 509998.05 |
| Authors | Diver, M.M.,Cheng, Y.,Julius, D. (deposition date: 2019-03-05, release date: 2019-09-18, Last modification date: 2024-03-20) |
| Primary citation | Diver, M.M.,Cheng, Y.,Julius, D. Structural insights into TRPM8 inhibition and desensitization. Science, 365:1434-1440, 2019 Cited by PubMed: 31488702DOI: 10.1126/science.aax6672 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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