6O69

Crystal Structure of Double Mutant L380R/F535K of Human Acetylcholinesterase

6O69 の概要

• エントリーDOI: 10.2210/pdb6o69/pdb
• 分子名称: Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 60043.69

構造登録者

Bester, S.M.,Height, J.J.,Pegan, S.D. (登録日: 2019-03-05, 公開日: 2019-05-01, 最終更新日: 2023-10-11)

• 主引用文献: Bester, S.M.,Adipietro, K.A.,Funk, V.L.,Myslinski, J.M.,Keul, N.D.,Cheung, J.,Wilder, P.T.,Wood, Z.A.,Weber, D.J.,Height, J.J.,Pegan, S.D.; The structural and biochemical impacts of monomerizing human acetylcholinesterase.; Protein Sci., 28:1106-1114, 2019; PubMed: 30993792; DOI: 10.1002/pro.3625

実験手法

X-RAY DIFFRACTION (2.081 Å)