6O5H
The effect of modifier structure on the activation of leukotriene A4 hydrolase aminopeptidase activity.
Summary for 6O5H
| Entry DOI | 10.2210/pdb6o5h/pdb |
| Descriptor | Leukotriene A-4 hydrolase, 4-{4-[(4-methoxyphenyl)methyl]phenyl}-1,3-thiazol-2-amine, ZINC ION, ... (4 entities in total) |
| Functional Keywords | leukotriene a4 hydrolase, 4-ome-arm1, aminipeptidase, activator, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 208105.03 |
| Authors | Noble, S.M.,Lee, K.H.,Paige, M. (deposition date: 2019-03-03, release date: 2019-12-04, Last modification date: 2024-03-13) |
| Primary citation | Lee, K.H.,Petruncio, G.,Shim, A.,Burdick, M.,Zhang, Z.,Shim, Y.M.,Noble, S.M.,Paige, M. Effect of Modifier Structure on the Activation of Leukotriene A4Hydrolase Aminopeptidase Activity. J.Med.Chem., 62:10605-10616, 2019 Cited by PubMed: 31751136DOI: 10.1021/acs.jmedchem.9b00663 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.84 Å) |
Structure validation
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