6O55

Crystal Structure of N5-carboxyaminoimidazole ribonucleotide mutase (PurE) from Legionella pneumophila

Summary for 6O55

Entry DOI	10.2210/pdb6o55/pdb
Descriptor	N5-carboxyaminoimidazole ribonucleotide mutase, 1,2-ETHANEDIOL, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	ssgcid, mutase, carboxylase, phosphorobosylaminoimidazole carboxylase, structural genomics, seattle structural genomics center for infectious disease, isomerase
Biological source	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
Total number of polymer chains	4
Total formula weight	75018.15
Authors	Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2019-03-01, release date: 2019-03-13, Last modification date: 2024-05-29)
Primary citation	Belfon, K.K.J.,Sharma, N.,Zigweid, R.,Bolejack, M.,Davies, D.,Edwards, T.E.,Myler, P.J.,French, J.B. Structure-Guided Discovery of N 5 -CAIR Mutase Inhibitors. Biochemistry, 62:2587-2596, 2023 Cited by PubMed: 37552766 DOI: 10.1021/acs.biochem.2c00705 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation