Room temperature structure of binary complex of native hAChE with BW284c51

Summary for 6O52

Related6o4w 6o4x 6o50
DescriptorAcetylcholinesterase, 4-(5-{4-[DIMETHYL(PROP-2-ENYL)AMMONIO]PHENYL}-3-OXOPENTYL)-N,N-DIMETHYL-N-PROP-2-ENYLBENZENAMINIUM (3 entities in total)
Functional Keywordsbw284c51, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight121389.16
Gerlits, O.,Kovalevsky, A.,Radic, Z. (deposition date: 2019-03-01, release date: 2019-06-19, Last modification date: 2019-07-10)
Primary citation
Gerlits, O.,Ho, K.Y.,Cheng, X.,Blumenthal, D.,Taylor, P.,Kovalevsky, A.,Radic, Z.
A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies.
Chem.Biol.Interact., 309:108698-108698, 2019
PubMed: 31176713 (PDB entries with the same primary citation)
DOI: 10.1016/j.cbi.2019.06.011
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1895 0.1% 0.8% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report