6O4W

Binary complex of native hAChE with Donepezil

6O4W の概要

分子名称Acetylcholinesterase, GLYCEROL, 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE, ... (5 entities in total)
機能のキーワードhydrolase
由来する生物種Homo sapiens (Human)
ポリマー鎖数2
分子量合計122135.52
構造登録者
Gerlits, O.,Kovalevsky, A.,Radic, Z. (登録日: 2019-03-01, 公開日: 2019-06-19, 最終更新日: 2019-07-10)
主引用文献
Gerlits, O.,Ho, K.Y.,Cheng, X.,Blumenthal, D.,Taylor, P.,Kovalevsky, A.,Radic, Z.
A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies.
Chem.Biol.Interact., 309:108698-108698, 2019
PubMed: 31176713 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.cbi.2019.06.011
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.35 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.18630 1.1% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード