6O2W

Crystal structure of the SARAF luminal domain Cys-lock mutant dimer

Summary for 6O2W

Entry DOI	10.2210/pdb6o2w/pdb
Related	6O2U 6O2V
Descriptor	Store-operated calcium entry-associated regulatory factor, GLYCEROL (3 entities in total)
Functional Keywords	soce, store operated calcium entry, saraf, er, endoplasmic reticulum, calcium signaling, domain swap, signaling protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	31138.76
Authors	Kimberlin, C.R.,Minor, D.L. (deposition date: 2019-02-24, release date: 2019-05-29, Last modification date: 2023-10-11)
Primary citation	Kimberlin, C.R.,Meshcheriakova, A.,Palty, R.,Raveh, A.,Karbat, I.,Reuveny, E.,Minor Jr., D.L. SARAF Luminal Domain Structure Reveals a Novel Domain-Swapped beta-Sandwich Fold Important for SOCE Modulation. J.Mol.Biol., 431:2869-2883, 2019 Cited by PubMed: 31082439 DOI: 10.1016/j.jmb.2019.05.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.101 Å)

Structure validation