6O2L
NMR structure of the 2:1 complex of a carbazole derivative BMVC bound to c-MYC G-quadruplex
Summary for 6O2L
Entry DOI | 10.2210/pdb6o2l/pdb |
NMR Information | BMRB: 30577 |
Descriptor | DNA (5'-D(*TP*GP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*AP*A)-3'), 3,6-bis[(E)-2-(1-methylpyridin-1-ium-4-yl)ethenyl]-9H-carbazole (2 entities in total) |
Functional Keywords | g-quadruplex dna, drug-dna complex, bmvc, dna |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 7815.55 |
Authors | |
Primary citation | Liu, W.,Lin, C.,Wu, G.,Dai, J.,Chang, T.C.,Yang, D. Structures of 1:1 and 2:1 complexes of BMVC and MYC promoter G-quadruplex reveal a mechanism of ligand conformation adjustment for G4-recognition. Nucleic Acids Res., 47:11931-11942, 2019 Cited by PubMed: 31740959DOI: 10.1093/nar/gkz1015 PDB entries with the same primary citation |
Experimental method |
Structure validation
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