6O26

Crystal structure of 3246 Fab in complex with circumsporozoite protein NANA

Summary for 6O26

• Entry DOI: 10.2210/pdb6o26/pdb
• Related: 6O23 6O24 6O25
• Descriptor: 3246 Fab heavy chain, 3246 Fab light chain, Circumsporozoite protein, ... (7 entities in total)
• Functional Keywords: malaria, antibody, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 48665.08

Authors

Scally, S.W.,Bosch, A.,Castro, K.,Murugan, R.,Wardemann, H.,Julien, J.P. (deposition date: 2019-02-22, release date: 2020-03-04, Last modification date: 2020-09-16)

• Primary citation: Murugan, R.,Scally, S.W.,Costa, G.,Mustafa, G.,Thai, E.,Decker, T.,Bosch, A.,Prieto, K.,Levashina, E.A.,Julien, J.P.,Wardemann, H.; Evolution of protective human antibodies against Plasmodium falciparum circumsporozoite protein repeat motifs.; Nat. Med., 26:1135-1145, 2020; PubMed: 32451496; DOI: 10.1038/s41591-020-0881-9

Experimental method

X-RAY DIFFRACTION (1.8 Å)