6NV8

Perdeuterated tyrosine phenol-lyase from Citrobacter freundii complexed with an aminoacrylate intermediate formed from S-ethyl-L-cysteine and 4-hydroxypyridine

6NV8 の概要

• エントリーDOI: 10.2210/pdb6nv8/pdb
• 分子名称: Tyrosine phenol-lyase, POTASSIUM ION, pyridin-4-ol, ... (8 entities in total)
• 機能のキーワード: pyridoxal-5'-phosphate, aminoacrylate intermediate, 4-hydroxypyridine, lyase, lyase-lyase inhibitor complex, lyase/lyase inhibitor
• 由来する生物種: Citrobacter freundii; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 104454.84

構造登録者

Phillips, R.S. (登録日: 2019-02-04, 公開日: 2020-02-12, 最終更新日: 2023-11-15)

• 主引用文献: Phillips, R.S.,Craig, S.,Kovalevsky, A.,Gerlits, O.,Weiss, K.,Iorgu, A.I.,Heyes, D.J.,Hay, S.; Pressure and Temperature Effects on the Formation of Aminoacrylate Intermediates of Tyrosine Phenol-lyase Demonstrate Reaction Dynamics; Acs Catalysis, 10:1692-1703, 2020; DOI: 10.1021/acscatal.9b03967

実験手法

X-RAY DIFFRACTION (2.26 Å)