6NU6

Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 5

Summary for 6NU6

• Entry DOI: 10.2210/pdb6nu6/pdb
• Related: 6CVE
• Descriptor: ATP-dependent dethiobiotin synthetase BioD, 4-[(1R,2S)-2-(carboxymethyl)cyclopentane-1-carbonyl]benzoic acid, 4-[(1S,2R)-2-(carboxymethyl)cyclopentane-1-carbonyl]benzoic acid, ... (5 entities in total)
• Functional Keywords: enzyme, synthetase, nucleotide triphosphate binding, transferase, ligase
• Biological source: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• Total number of polymer chains: 4
• Total formula weight: 95737.19

Authors

Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B. (deposition date: 2019-01-31, release date: 2020-02-05, Last modification date: 2023-10-11)

• Primary citation: Thompson, A.P.,Polyak, S.W.,Wegener, K.L.,Bruning, J.B.; Crystal structure of Mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 5; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.437 Å)