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6NT5

Cryo-EM structure of full-length human STING in the apo state

Summary for 6NT5
Entry DOI10.2210/pdb6nt5/pdb
EMDB information0502
DescriptorStimulator of interferon protein (1 entity in total)
Functional Keywordser, membrane, adaptor, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight85970.76
Authors
Shang, G.,Zhang, C.,Chen, Z.J.,Bai, X.,Zhang, X. (deposition date: 2019-01-28, release date: 2019-03-06, Last modification date: 2024-03-20)
Primary citationShang, G.,Zhang, C.,Chen, Z.J.,Bai, X.C.,Zhang, X.
Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP.
Nature, 567:389-393, 2019
Cited by
PubMed: 30842659
DOI: 10.1038/s41586-019-0998-5
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4.1 Å)
Structure validation

217705

건을2024-03-27부터공개중

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