6NT5
Cryo-EM structure of full-length human STING in the apo state
Summary for 6NT5
Entry DOI | 10.2210/pdb6nt5/pdb |
EMDB information | 0502 |
Descriptor | Stimulator of interferon protein (1 entity in total) |
Functional Keywords | er, membrane, adaptor, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 85970.76 |
Authors | Shang, G.,Zhang, C.,Chen, Z.J.,Bai, X.,Zhang, X. (deposition date: 2019-01-28, release date: 2019-03-06, Last modification date: 2024-03-20) |
Primary citation | Shang, G.,Zhang, C.,Chen, Z.J.,Bai, X.C.,Zhang, X. Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMP. Nature, 567:389-393, 2019 Cited by PubMed: 30842659DOI: 10.1038/s41586-019-0998-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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