6NIH

Crystal structure of human TLR1

Summary for 6NIH

• Entry DOI: 10.2210/pdb6nih/pdb
• Related PRD ID: PRD_900017
• Descriptor: Toll-like receptor 1,Variable lymphocyte receptor B, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: toll-like receptors, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 127257.99

Authors

Su, L.,Zhang, H. (deposition date: 2018-12-27, release date: 2019-04-17, Last modification date: 2023-10-11)

• Primary citation: Su, L.,Wang, Y.,Wang, J.,Mifune, Y.,Morin, M.D.,Jones, B.T.,Moresco, E.M.Y.,Boger, D.L.,Beutler, B.,Zhang, H.; Structural Basis of TLR2/TLR1 Activation by the Synthetic Agonist Diprovocim.; J. Med. Chem., 62:2938-2949, 2019; PubMed: 30829478; DOI: 10.1021/acs.jmedchem.8b01583

Experimental method

X-RAY DIFFRACTION (2.3 Å)