6NEF

Outer Membrane Cytochrome S Filament from Geobacter Sulfurreducens

6NEF の概要

• エントリーDOI: 10.2210/pdb6nef/pdb
• EMDBエントリー: 9357
• 分子名称: C-type cytochrome OmcS, HEME C, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: conductive, filament, nanowire, six-heme multiheme c-type cytochrome, protein fibril
• 由来する生物種: Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46721.33

構造登録者

Filman, D.J.,Marino, S.F.,Ward, J.E.,Yang, L.,Mester, Z.,Bullitt, E.,Lovley, D.R.,Strauss, M. (登録日: 2018-12-17, 公開日: 2019-07-03, 最終更新日: 2024-10-23)

主引用文献

Filman, D.J.,Marino, S.F.,Ward, J.E.,Yang, L.,Mester, Z.,Bullitt, E.,Lovley, D.R.,Strauss, M.
Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.
Commun Biol, 2:219-219, 2019

PubMed Abstract: Electrically conductive pili from species, termed bacterial nanowires, are intensely studied for their biological significance and potential in the development of new materials. Using cryo-electron microscopy, we have characterized nanowires from conductive pili preparations that are composed solely of head-to-tail stacked monomers of the six-heme C-type cytochrome OmcS. The unique fold of OmcS - closely wrapped around a continuous stack of hemes that can serve as an uninterrupted path for electron transport - generates a scaffold that supports the unbranched chain of hemes along the central axis of the filament. We present here, at 3.4 Å resolution, the structure of this cytochrome-based filament and discuss its possible role in long-range biological electron transport.

PubMed: 31240257
DOI: 10.1038/s42003-019-0448-9

実験手法

ELECTRON MICROSCOPY (3.4 Å)