6NEE
Crystal structure of a reconstructed ancestor of Triosephosphate isomerase from eukaryotes
Summary for 6NEE
Entry DOI | 10.2210/pdb6nee/pdb |
Descriptor | TRIOSEPHOSPHATE ISOMERASE, PHOSPHOGLYCOLOHYDROXAMIC ACID (3 entities in total) |
Functional Keywords | isomerase, glycolisis, tim barrel, ancestral sequence reconstruction |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 55419.46 |
Authors | Rodriguez-Romero, A.,Schulte-Sasse, M.,Fernandez-Velasco, D.A. (deposition date: 2018-12-17, release date: 2019-01-09, Last modification date: 2023-10-11) |
Primary citation | Schulte-Sasse, M.,Pardo-Avila, F.,Pulido-Mayoral, N.O.,Vazquez-Lobo, A.,Costas, M.,Garcia-Hernandez, E.,Rodriguez-Romero, A.,Fernandez-Velasco, D.A. Structural, thermodynamic and catalytic characterization of an ancestral triosephosphate isomerase reveal early evolutionary coupling between monomer association and function. FEBS J., 286:882-900, 2019 Cited by PubMed: 30589511DOI: 10.1111/febs.14741 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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