6NEA

Human Acetylcholinesterase in complex with reactivator, HLo7

Summary for 6NEA

Entry DOI	10.2210/pdb6nea/pdb
Descriptor	Acetylcholinesterase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	121746.94
Authors	Bester, S.M.,McGuire, J.,Height, J.J.,Pegan, S.D. (deposition date: 2018-12-17, release date: 2019-06-12, Last modification date: 2023-10-11)
Primary citation	Hsu, F.L.,Bae, S.Y.,McGuire, J.,Anderson, D.R.,Bester, S.M.,Height, J.J.,Pegan, S.D.,Walz, A.J. Synthesis and Molecular Properties of Nerve Agent Reactivator HLo-7 Dimethanesulfonate. Acs Med.Chem.Lett., 10:761-766, 2019 Cited by PubMed: 31097996 DOI: 10.1021/acsmedchemlett.9b00021 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.419 Å)

Structure validation