6NCP
Crystal structure of HIV-1 broadly neutralizing antibody ACS202
Summary for 6NCP
Entry DOI | 10.2210/pdb6ncp/pdb |
Related | 6NC2 6NC3 |
EMDB information | 0433 0434 |
Descriptor | ACS202 Fab heavy chain, ACS202 Fab light chain, HIV-1 Fusion Peptide (residues 512-520), ... (7 entities in total) |
Functional Keywords | antibody, hiv, envelope glycoprotein, fusion peptide, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 99449.40 |
Authors | Yuan, M.,Wilson, I.A. (deposition date: 2018-12-11, release date: 2019-06-19, Last modification date: 2023-10-11) |
Primary citation | Yuan, M.,Cottrell, C.A.,Ozorowski, G.,van Gils, M.J.,Kumar, S.,Wu, N.C.,Sarkar, A.,Torres, J.L.,de Val, N.,Copps, J.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25:873-883.e5, 2019 Cited by PubMed: 31194940DOI: 10.1016/j.chom.2019.04.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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