6NCE

Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead DNA sequence

6NCE の概要

• エントリーDOI: 10.2210/pdb6nce/pdb
• 分子名称: Forkhead box protein N3, DNA (5'-D(*TP*CP*TP*TP*AP*AP*GP*TP*AP*AP*AP*CP*AP*AP*TP*G)-3'), DNA (5'-D(*AP*CP*AP*TP*TP*GP*TP*TP*TP*AP*CP*TP*TP*AP*AP*G)-3'), ... (6 entities in total)
• 機能のキーワード: sequence specific dna binding, regulation of transcription dna templated, dna binding transcription factor activity, forkhead, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 21610.63

構造登録者

Rogers, J.M.,Jarrett, S.M.,Seegar, T.C.,Waters, C.T.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L. (登録日: 2018-12-11, 公開日: 2019-02-27, 最終更新日: 2023-10-11)

• 主引用文献: Rogers, J.M.,Waters, C.T.,Seegar, T.C.M.,Jarrett, S.M.,Hallworth, A.N.,Blacklow, S.C.,Bulyk, M.L.; Bispecific Forkhead Transcription Factor FoxN3 Recognizes Two Distinct Motifs with Different DNA Shapes.; Mol. Cell, 74:245-, 2019; PubMed: 30826165; DOI: 10.1016/j.molcel.2019.01.019

実験手法

X-RAY DIFFRACTION (2.598 Å)