6NC3
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding
This is a non-PDB format compatible entry.
Summary for 6NC3
Entry DOI | 10.2210/pdb6nc3/pdb |
EMDB information | 0434 |
Descriptor | HIV-1 Env AMC011 v4.2 SOSIP gp120, HIV-1 Env AMC011 v4.2 SOSIP gp41, Monoclonal antibody VRC34.01 fragment antigen binding heavy chain, ... (9 entities in total) |
Functional Keywords | hiv-1 env, sosip, trimer, broadly neutralizing antibody, fusion peptide, viral protein, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 24 |
Total formula weight | 760646.34 |
Authors | Cottrell, C.A.,Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2018-12-10, release date: 2019-06-19, Last modification date: 2024-10-09) |
Primary citation | Yuan, M.,Cottrell, C.A.,Ozorowski, G.,van Gils, M.J.,Kumar, S.,Wu, N.C.,Sarkar, A.,Torres, J.L.,de Val, N.,Copps, J.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25:873-, 2019 Cited by PubMed: 31194940DOI: 10.1016/j.chom.2019.04.011 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.5 Å) |
Structure validation
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