6NC2
AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding
Summary for 6NC2
Entry DOI | 10.2210/pdb6nc2/pdb |
EMDB information | 0433 |
Descriptor | AMC011 v4.2 SOSIP gp120, AMC011 v4.2 SOSIP gp41, Monoclonal antibody ACS202 fragment antigen binding heavy chain, ... (8 entities in total) |
Functional Keywords | hiv-1 env, sosip, trimer, broadly neutralizing antibody, fusion peptide, viral protein, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 24 |
Total formula weight | 793574.02 |
Authors | Cottrell, C.A.,Ozorowski, G.,Yuan, M.,Copps, J.,Wilson, I.A.,Ward, A.B. (deposition date: 2018-12-10, release date: 2019-06-19, Last modification date: 2020-07-29) |
Primary citation | Yuan, M.,Cottrell, C.A.,Ozorowski, G.,van Gils, M.J.,Kumar, S.,Wu, N.C.,Sarkar, A.,Torres, J.L.,de Val, N.,Copps, J.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25:873-, 2019 Cited by PubMed: 31194940DOI: 10.1016/j.chom.2019.04.011 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (5.2 Å) |
Structure validation
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