6NC2

AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding

Summary for 6NC2

Entry DOI	10.2210/pdb6nc2/pdb
EMDB information	0433
Descriptor	AMC011 v4.2 SOSIP gp120, AMC011 v4.2 SOSIP gp41, Monoclonal antibody ACS202 fragment antigen binding heavy chain, ... (8 entities in total)
Functional Keywords	hiv-1 env, sosip, trimer, broadly neutralizing antibody, fusion peptide, viral protein, immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	24
Total formula weight	793574.02
Authors	Cottrell, C.A.,Ozorowski, G.,Yuan, M.,Copps, J.,Wilson, I.A.,Ward, A.B. (deposition date: 2018-12-10, release date: 2019-06-19, Last modification date: 2020-07-29)
Primary citation	Yuan, M.,Cottrell, C.A.,Ozorowski, G.,van Gils, M.J.,Kumar, S.,Wu, N.C.,Sarkar, A.,Torres, J.L.,de Val, N.,Copps, J.,Moore, J.P.,Sanders, R.W.,Ward, A.B.,Wilson, I.A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25:873-, 2019 Cited by PubMed: 31194940 DOI: 10.1016/j.chom.2019.04.011 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.2 Å)

Structure validation