6NBI
Cryo-EM structure of parathyroid hormone receptor type 1 in complex with a long-acting parathyroid hormone analog and G protein
Summary for 6NBI
Entry DOI | 10.2210/pdb6nbi/pdb |
EMDB information | 0412 4010 4011 |
Descriptor | Parathyroid hormone/parathyroid hormone-related peptide receptor, Long-acting parathyroid hormone analog, Gs protein alpha subunit, ... (7 entities in total) |
Functional Keywords | parathyroid hormone receptor, gpcr, class b gpcr, gpcr-g protein complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 163544.68 |
Authors | Zhao, L.-H.,Ma, S.,Sutkeviciute, I.,Shen, D.-D.,Zhou, X.E.,de Waal, P.P.,Li, C.-Y.,Kang, Y.,Clark, L.J.,Jean-Alphonse, F.G.,White, A.D.,Xiao, K.,Yang, D.,Jiang, Y.,Watanabe, T.,Gardella, T.J.,Melcher, K.,Wang, M.-W.,Vilardaga, J.-P.,Xu, H.E.,Zhang, Y. (deposition date: 2018-12-07, release date: 2019-04-17, Last modification date: 2019-12-18) |
Primary citation | Zhao, L.H.,Ma, S.,Sutkeviciute, I.,Shen, D.D.,Zhou, X.E.,de Waal, P.W.,Li, C.Y.,Kang, Y.,Clark, L.J.,Jean-Alphonse, F.G.,White, A.D.,Yang, D.,Dai, A.,Cai, X.,Chen, J.,Li, C.,Jiang, Y.,Watanabe, T.,Gardella, T.J.,Melcher, K.,Wang, M.W.,Vilardaga, J.P.,Xu, H.E.,Zhang, Y. Structure and dynamics of the active human parathyroid hormone receptor-1. Science, 364:148-153, 2019 Cited by PubMed: 30975883DOI: 10.1126/science.aav7942 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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