6NB8

Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment

Summary for 6NB8

• Entry DOI: 10.2210/pdb6nb8/pdb
• Descriptor: S230 antigen-binding (Fab) fragment, heavy chain, S230 antigen-binding (Fab) fragment, light chain (3 entities in total)
• Functional Keywords: fab, coronavirus, sars, glycoprotein, structural genomics, seattle structural genomics center for infectious disease, ssgcid, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 48972.53

Authors

Walls, A.J.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, J.,Quispe, J.,Cameroni, E.,Gopal, R.,Dai, M.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-12-06, release date: 2019-02-06, Last modification date: 2023-10-11)

• Primary citation: Walls, A.C.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, J.,Quispe, J.,Cameroni, E.,Gopal, R.,Dai, M.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D.; Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.; Cell, 176:1026-1039.e15, 2019; PubMed: 30712865; DOI: 10.1016/j.cell.2018.12.028

Experimental method

X-RAY DIFFRACTION (1.5 Å)