6NB5
Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment
Summary for 6NB5
Entry DOI | 10.2210/pdb6nb5/pdb |
Descriptor | LCA60 antigen-binding (Fab) fragment, heavy chain, LCA60 antigen-binding (Fab) fragment, light chain (2 entities in total) |
Functional Keywords | fab, coronavirus, mers-cov, glycoprotein, structural genomics, seattle structural genomics center for infectious disease, ssgcid, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 94124.91 |
Authors | Walls, A.J.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, J.,Quispe, J.,Cameroni, E.,Gopal, R.,Dai, M.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2018-12-06, release date: 2019-02-06, Last modification date: 2023-10-11) |
Primary citation | Walls, A.C.,Xiong, X.,Park, Y.J.,Tortorici, M.A.,Snijder, J.,Quispe, J.,Cameroni, E.,Gopal, R.,Dai, M.,Lanzavecchia, A.,Zambon, M.,Rey, F.A.,Corti, D.,Veesler, D. Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176:1026-1039.e15, 2019 Cited by PubMed: 30712865DOI: 10.1016/j.cell.2018.12.028 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
Download full validation report