6NAY

Crystal structure of Neisseria meningitidis ClpP protease E31A+E58A activated double mutant

Summary for 6NAY

Entry DOI	10.2210/pdb6nay/pdb
Related	6NAH 6NAQ 6NAW
Descriptor	ATP-dependent Clp protease proteolytic subunit (2 entities in total)
Functional Keywords	serine protease, antibiotic, hydrolase
Biological source	Neisseria meningitidis
Total number of polymer chains	28
Total formula weight	680251.04
Authors	Mabanglo, M.F.,Houry, W.A. (deposition date: 2018-12-06, release date: 2019-11-13, Last modification date: 2023-10-11)
Primary citation	Mabanglo, M.F.,Leung, E.,Vahidi, S.,Seraphim, T.V.,Eger, B.T.,Bryson, S.,Bhandari, V.,Zhou, J.L.,Mao, Y.Q.,Rizzolo, K.,Barghash, M.M.,Goodreid, J.D.,Phanse, S.,Babu, M.,Barbosa, L.R.S.,Ramos, C.H.I.,Batey, R.A.,Kay, L.E.,Pai, E.F.,Houry, W.A. ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2:410-410, 2019 Cited by PubMed: 31925204 DOI: 10.1038/s42003-019-0656-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.199 Å)

Structure validation