6N9N

Crystal structure of murine GSDMD

Summary for 6N9N

• Entry DOI: 10.2210/pdb6n9n/pdb
• Descriptor: Gasdermin-D (1 entity in total)
• Functional Keywords: pyroptosis, gasdermin d, inflammasome, autoinhibition, immune system
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 106753.57

Authors

Liu, Z.,Wang, C.,Yang, J.,Xiao, T.S. (deposition date: 2018-12-03, release date: 2019-06-05, Last modification date: 2023-10-11)

• Primary citation: Liu, Z.,Wang, C.,Yang, J.,Zhou, B.,Yang, R.,Ramachandran, R.,Abbott, D.W.,Xiao, T.S.; Crystal Structures of the Full-Length Murine and Human Gasdermin D Reveal Mechanisms of Autoinhibition, Lipid Binding, and Oligomerization.; Immunity, 51:43-, 2019; PubMed: 31097341; DOI: 10.1016/j.immuni.2019.04.017

Experimental method

X-RAY DIFFRACTION (3.3 Å)