6N9J
X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron in complex with an irreversible peptide inhibitor
Summary for 6N9J
Entry DOI | 10.2210/pdb6n9j/pdb |
Descriptor | Clostripain-related protein, Covalently bound peptide inhibitor (3 entities in total) |
Functional Keywords | c11 protease, secreted, covalent peptide inhibitor, microbiome, commensal, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) More |
Total number of polymer chains | 4 |
Total formula weight | 85858.65 |
Authors | Wolan, D.W.,Gonzalez-Paez, G.E.,Roncase, E.J. (deposition date: 2018-12-03, release date: 2019-12-11, Last modification date: 2023-11-15) |
Primary citation | Roncase, E.J.,Gonzalez-Paez, G.E.,Wolan, D.W. X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors. Biochemistry, 58:1728-1737, 2019 Cited by PubMed: 30835452DOI: 10.1021/acs.biochem.9b00098 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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