6N9J

X-ray structure of a secreted C11 cysteine protease from Bacteroides thetaiotaomicron in complex with an irreversible peptide inhibitor

6N9J の概要

• エントリーDOI: 10.2210/pdb6n9j/pdb
• 分子名称: Clostripain-related protein, Covalently bound peptide inhibitor (3 entities in total)
• 機能のキーワード: c11 protease, secreted, covalent peptide inhibitor, microbiome, commensal, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 85858.65

構造登録者

Wolan, D.W.,Gonzalez-Paez, G.E.,Roncase, E.J. (登録日: 2018-12-03, 公開日: 2019-12-11, 最終更新日: 2023-11-15)

• 主引用文献: Roncase, E.J.,Gonzalez-Paez, G.E.,Wolan, D.W.; X-ray Structures of Two Bacteroides thetaiotaomicron C11 Proteases in Complex with Peptide-Based Inhibitors.; Biochemistry, 58:1728-1737, 2019; PubMed: 30835452; DOI: 10.1021/acs.biochem.9b00098

実験手法

X-RAY DIFFRACTION (2.17 Å)