6N81

Crystal structure of GII.4 2002 norovirus P domain in complex with cross-reactive human antibody A1227

6N81 の概要

• エントリーDOI: 10.2210/pdb6n81/pdb
• 分子名称: Major capsid protein, A1227 Fab light chain, A1227 Fab heavy chain, ... (4 entities in total)
• 機能のキーワード: norovirus, human antibody, complex, fab, immune system
• 由来する生物種: Norovirus Hu/GII.4/Farmington Hills/2004/USA; 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 163922.68

構造登録者

Changela, A.,Verardi, R.,Kwong, P.D. (登録日: 2018-11-28, 公開日: 2019-06-19, 最終更新日: 2023-10-11)

• 主引用文献: Lindesmith, L.C.,McDaniel, J.R.,Changela, A.,Verardi, R.,Kerr, S.A.,Costantini, V.,Brewer-Jensen, P.D.,Mallory, M.L.,Voss, W.N.,Boutz, D.R.,Blazeck, J.J.,Ippolito, G.C.,Vinje, J.,Kwong, P.D.,Georgiou, G.,Baric, R.S.; Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination.; Immunity, 50:1530-1541.e8, 2019; PubMed: 31216462; DOI: 10.1016/j.immuni.2019.05.007

実験手法

X-RAY DIFFRACTION (2.579 Å)