6N7J

BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk

6N7J の概要

• エントリーDOI: 10.2210/pdb6n7j/pdb
• 分子名称: BDBV223 antibody heavy chain, BDBV223 antibody light chain, Envelope glycoprotein (3 entities in total)
• 機能のキーワード: antibody, antiviral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 100628.70

構造登録者

King, L.B.,West, B.R.,Saphire, E.O. (登録日: 2018-11-27, 公開日: 2019-03-20, 最終更新日: 2023-10-11)

• 主引用文献: King, L.B.,West, B.R.,Moyer, C.L.,Gilchuk, P.,Flyak, A.,Ilinykh, P.A.,Bombardi, R.,Hui, S.,Huang, K.,Bukreyev, A.,Crowe Jr., J.E.,Saphire, E.O.; Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk.; Nat Commun, 10:1788-1788, 2019; PubMed: 30996276; DOI: 10.1038/s41467-019-09732-7

実験手法

X-RAY DIFFRACTION (3.684 Å)