6N61
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin
Summary for 6N61
Entry DOI | 10.2210/pdb6n61/pdb |
Descriptor | DNA-directed RNA polymerase subunit alpha, MAGNESIUM ION, ZINC ION, ... (13 entities in total) |
Functional Keywords | capistruin, complex, inhibitor, lasso peptide, rna polymerase, transferase-dna complex, transferase/dna |
Biological source | Escherichia coli More |
Total number of polymer chains | 9 |
Total formula weight | 458573.02 |
Authors | Braffman, N.,Hauver, J.,Campbell, E.A.,Darst, S.A. (deposition date: 2018-11-24, release date: 2019-01-09, Last modification date: 2023-10-11) |
Primary citation | Braffman, N.R.,Piscotta, F.J.,Hauver, J.,Campbell, E.A.,Link, A.J.,Darst, S.A. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116:1273-1278, 2019 Cited by PubMed: 30626643DOI: 10.1073/pnas.1817352116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.253 Å) |
Structure validation
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