6N5E

Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope

Summary for 6N5E

DescriptorHemagglutinin, FL-1066 heavy chain, FL-1066 light chain, ... (4 entities in total)
Functional Keywordsinfluenza, antibody, complex, hemagglutinin, immunogen design, glycan, viral protein-immune system complex, viral protein/immune system
Biological sourceInfluenza A virus
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Total number of polymer chains9
Total molecular weight241396.52
Authors
Bajic, G.,Schmidt, A.G. (deposition date: 2018-11-21, release date: 2019-06-05, Last modification date: 2019-06-26)
Primary citation
Bajic, G.,Maron, M.J.,Adachi, Y.,Onodera, T.,McCarthy, K.R.,McGee, C.E.,Sempowski, G.D.,Takahashi, Y.,Kelsoe, G.,Kuraoka, M.,Schmidt, A.G.
Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope.
Cell Host Microbe, 25:827-, 2019
PubMed: 31104946 (PDB entries with the same primary citation)
DOI: 10.1016/j.chom.2019.04.003
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.28329 0.6% 4.4% 1.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution