6N4X

Metabotropic Glutamate Receptor 5 Apo Form Ligand Binding Domain

Summary for 6N4X

Entry DOI	10.2210/pdb6n4x/pdb
Descriptor	Metabotropic glutamate receptor 5, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION (3 entities in total)
Functional Keywords	cell surface receptor, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	198365.24
Authors	Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Weis, W.I.,Skiniotis, G.S.,Mathiesen, J.M.,Kobilka, B.K. (deposition date: 2018-11-20, release date: 2019-01-23, Last modification date: 2023-10-11)
Primary citation	Koehl, A.,Hu, H.,Feng, D.,Sun, B.,Zhang, Y.,Robertson, M.J.,Chu, M.,Kobilka, T.S.,Laermans, T.,Steyaert, J.,Tarrasch, J.,Dutta, S.,Fonseca, R.,Weis, W.I.,Mathiesen, J.M.,Skiniotis, G.,Kobilka, B.K. Structural insights into the activation of metabotropic glutamate receptors. Nature, 566:79-84, 2019 Cited by PubMed: 30675062 DOI: 10.1038/s41586-019-0881-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (4 Å)

Structure validation