6N37
SegA-sym, conformation of TDP-43 low complexity domain segment A sym
Summary for 6N37
Entry DOI | 10.2210/pdb6n37/pdb |
EMDB information | 9339 |
Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
Functional Keywords | amyloid, tdp43, als, ftld-tdp, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 10 |
Total formula weight | 52077.97 |
Authors | Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-11-14, release date: 2019-06-26, Last modification date: 2024-03-20) |
Primary citation | Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Ge, P.,Eisenberg, D.S. Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26:619-627, 2019 Cited by PubMed: 31235914DOI: 10.1038/s41594-019-0248-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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