Summary for 6N1I
Entry DOI | 10.2210/pdb6n1i/pdb |
EMDB information | 8902 8903 |
Descriptor | NLR family CARD domain-containing protein 4 (1 entity in total) |
Functional Keywords | inflammasome, filament, immunity, signaling protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 16 |
Total formula weight | 159802.74 |
Authors | |
Primary citation | Li, Y.,Fu, T.M.,Lu, A.,Witt, K.,Ruan, J.,Shen, C.,Wu, H. Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1. Proc. Natl. Acad. Sci. U.S.A., 115:10845-10852, 2018 Cited by PubMed: 30279182DOI: 10.1073/pnas.1810524115 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.58 Å) |
Structure validation
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