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6N0Y

Crystal structure of Anaerolinea thermophila mevalonate 5-phosphate decarboxylase complexed with (R)-MVAPP

Summary for 6N0Y
Entry DOI10.2210/pdb6n0y/pdb
DescriptorDiphosphomevalonate decarboxylase, (3R)-3-HYDROXY-5-{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}-3-METHYLPENTANOIC ACID (3 entities in total)
Functional Keywordslyase
Biological sourceAnaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1)
Total number of polymer chains6
Total formula weight216316.57
Authors
Noel, J.P.,Thomas, S.T.,Louie, G.V. (deposition date: 2018-11-07, release date: 2019-07-17, Last modification date: 2023-10-11)
Primary citationThomas, S.T.,Louie, G.V.,Lubin, J.W.,Lundblad, V.,Noel, J.P.
Substrate Specificity and Engineering of Mevalonate 5-Phosphate Decarboxylase.
Acs Chem.Biol., 14:1767-1779, 2019
Cited by
PubMed: 31268677
DOI: 10.1021/acschembio.9b00322
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

数据于2024-03-27公开中

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