6MYE

Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)

6MYE の概要

• エントリーDOI: 10.2210/pdb6mye/pdb
• 分子名称: Protein scribble homolog, Rho guanine nucleotide exchange factor 26, peptide, FORMIC ACID, ... (4 entities in total)
• 機能のキーワード: guanyl nucleotide exchange factor, sgef/scribble/dlg1 compelx, cell adhesion, tight junction
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 11182.62

構造登録者

Sun, Y.J.,Hou, T.,Gakhar, L.,Fuentes, E.J. (登録日: 2018-11-01, 公開日: 2019-04-10, 最終更新日: 2023-10-11)

• 主引用文献: Awadia, S.,Huq, F.,Arnold, T.R.,Goicoechea, S.M.,Sun, Y.J.,Hou, T.,Kreider-Letterman, G.,Massimi, P.,Banks, L.,Fuentes, E.J.,Miller, A.L.,Garcia-Mata, R.; SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility.; J.Cell Biol., 218:2699-2725, 2019; PubMed: 31248911; DOI: 10.1083/jcb.201811114

実験手法