6MYE
Crystal structure of human Scribble PDZ1 domain in complex with internal PDZ binding motif of Src homology 3 domain-containing guanine nucleotide exchange factor (SGEF)
6MYE の概要
エントリーDOI | 10.2210/pdb6mye/pdb |
分子名称 | Protein scribble homolog, Rho guanine nucleotide exchange factor 26, peptide, FORMIC ACID, ... (4 entities in total) |
機能のキーワード | guanyl nucleotide exchange factor, sgef/scribble/dlg1 compelx, cell adhesion, tight junction |
由来する生物種 | Homo sapiens (Human) 詳細 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 11182.62 |
構造登録者 | |
主引用文献 | Awadia, S.,Huq, F.,Arnold, T.R.,Goicoechea, S.M.,Sun, Y.J.,Hou, T.,Kreider-Letterman, G.,Massimi, P.,Banks, L.,Fuentes, E.J.,Miller, A.L.,Garcia-Mata, R. SGEF forms a complex with Scribble and Dlg1 and regulates epithelial junctions and contractility. J.Cell Biol., 218:2699-2725, 2019 Cited by PubMed: 31248911DOI: 10.1083/jcb.201811114 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.1 Å) |
構造検証レポート
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