6MWZ
LasR LBD T75V/Y93F/A127W:BB0126
Summary for 6MWZ
Entry DOI | 10.2210/pdb6mwz/pdb |
Descriptor | Transcriptional regulator LasR, ALA-HIS-HIS-HIS-HIS-ALA, 4-[3-(methylsulfonyl)phenoxy]-N-[(1S,3S,5S)-2-oxobicyclo[3.1.0]hexan-3-yl]butanamide, ... (4 entities in total) |
Functional Keywords | transcriptional activator, transcription |
Biological source | Pseudomonas aeruginosa (strain UCBPP-PA14) More |
Total number of polymer chains | 3 |
Total formula weight | 54904.94 |
Authors | Bassler, B.L.,Paczkowski, J.E. (deposition date: 2018-10-30, release date: 2019-04-03, Last modification date: 2024-03-13) |
Primary citation | Paczkowski, J.E.,McCready, A.R.,Cong, J.P.,Li, Z.,Jeffrey, P.D.,Smith, C.D.,Henke, B.R.,Hughson, F.M.,Bassler, B.L. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. Acs Chem.Biol., 14:378-389, 2019 Cited by PubMed: 30763066DOI: 10.1021/acschembio.8b00971 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.657 Å) |
Structure validation
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