6MWI

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) Burkholderia pseudomallei in complex with ligand HGN-0456

6MWI の概要

• エントリーDOI: 10.2210/pdb6mwi/pdb
• 分子名称: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total)
• 機能のキーワード: ssgcid, structural genomics, seattle structural genomics center for infectious disease, lyase
• 由来する生物種: Burkholderia pseudomallei (strain 1710b)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 53263.62

構造登録者

Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2018-10-29, 公開日: 2019-11-06, 最終更新日: 2025-04-09)

• 主引用文献: Grote, D.,Stewart, C.G.,Daraji, D.G.,Enayati, P.,Braverman, K.N.,Romanaggi, C.,Bolejack, M.J.,Yano, J.K.,Abendroth, J.,Dranow, D.M.,Pierce, P.G.,Lorimer, D.D.,Horanyi, P.S.,Staker, B.L.,Edwards, T.E.,Myler, P.J.,Horn, J.R.,Hagen, T.J.; Analysis of Burkholderia pseudomallei IspF in complex with sulfapyridine, sulfamonomethoxine, ethoxzolamide and acetazolamide; Acta Crystallogr.,Sect.F, 81:138-145, 2025

実験手法

X-RAY DIFFRACTION (1.75 Å)