6MV2

2.05A resolution structure of the CS-b5R domains of human Ncb5or (NADP+ form)

6MV2 の概要

• エントリーDOI: 10.2210/pdb6mv2/pdb
• 分子名称: Cytochrome b5 reductase 4, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
• 機能のキーワード: ncb5or, electron transfer, redox, heme, endoplasmic reticulum, flavoprotein, iron, metal-binding, oxidoreductase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43648.46

構造登録者

Lovell, S.,Mehzabeen, N.,Battaile, K.P.,Benson, D.R.,Cooper, A.,Gao, P.,Zhu, H. (登録日: 2018-10-24, 公開日: 2019-07-17, 最終更新日: 2023-10-11)

• 主引用文献: Benson, D.R.,Lovell, S.,Mehzabeen, N.,Galeva, N.,Cooper, A.,Gao, P.,Battaile, K.P.,Zhu, H.; Crystal structures of the naturally fused CS and cytochrome b5reductase (b5R) domains of Ncb5or reveal an expanded CS fold, extensive CS-b5R interactions and productive binding of the NAD(P)+nicotinamide ring.; Acta Crystallogr D Struct Biol, 75:628-638, 2019; PubMed: 31282472; DOI: 10.1107/S205979831900754X

実験手法

X-RAY DIFFRACTION (2.05 Å)