6MPI

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin

Summary for 6MPI

Entry DOI	10.2210/pdb6mpi/pdb
Descriptor	16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (26 entities in total)
Functional Keywords	2-thiocytidine, inosine, transfer rna, trna, ribosome, 30s, translation, anticodon
Biological source	Thermus thermophilus HB8 More
Total number of polymer chains	23
Total formula weight	789003.87
Authors	Cantara, W.A.,DeMirci, H.,Agris, P.F. (deposition date: 2018-10-07, release date: 2019-04-24, Last modification date: 2023-10-11)
Primary citation	Vangaveti, S.,Cantara, W.A.,Spears, J.L.,DeMirci, H.,Murphy IV, F.V.,Ranganathan, S.V.,Sarachan, K.L.,Agris, P.F. A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432:913-929, 2020 Cited by PubMed: 31945376 DOI: 10.1016/j.jmb.2019.12.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.33 Å)

Structure validation