6MPI

Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin

6MPI の概要

• エントリーDOI: 10.2210/pdb6mpi/pdb
• 分子名称: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (26 entities in total)
• 機能のキーワード: 2-thiocytidine, inosine, transfer rna, trna, ribosome, 30s, translation, anticodon
• 由来する生物種: Thermus thermophilus HB8; 詳細
• タンパク質・核酸の鎖数: 23
• 化学式量合計: 789003.87

構造登録者

Cantara, W.A.,DeMirci, H.,Agris, P.F. (登録日: 2018-10-07, 公開日: 2019-04-24, 最終更新日: 2023-10-11)

• 主引用文献: Vangaveti, S.,Cantara, W.A.,Spears, J.L.,DeMirci, H.,Murphy IV, F.V.,Ranganathan, S.V.,Sarachan, K.L.,Agris, P.F.; A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine.; J.Mol.Biol., 432:913-929, 2020; PubMed: 31945376; DOI: 10.1016/j.jmb.2019.12.016

実験手法

X-RAY DIFFRACTION (3.33 Å)