6MP4

Human liver FABP1 bound to tetrahydrocannabinol

Summary for 6MP4

Entry DOI	10.2210/pdb6mp4/pdb
Descriptor	Fatty acid-binding protein, liver, MALONATE ION, (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,8,10a-tetrahydro-6H-benzo[c]chromen-1-ol, ... (4 entities in total)
Functional Keywords	fatty acid binding protein cannabinoid, lipid binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	8
Total formula weight	135530.46
Authors	McGoldrick, L.L.,Giuliano, C.J.,Elmes, M.W.,Deutsch, D.G.,Kaczocha, M.,Glynn, S.E. (deposition date: 2018-10-05, release date: 2019-11-13, Last modification date: 2024-04-03)
Primary citation	Elmes, M.W.,Prentis, L.E.,McGoldrick, L.L.,Giuliano, C.J.,Sweeney, J.M.,Joseph, O.M.,Che, J.,Carbonetti, G.S.,Studholme, K.,Deutsch, D.G.,Rizzo, R.C.,Glynn, S.E.,Kaczocha, M. FABP1 controls hepatic transport and biotransformation of Delta 9 -THC. Sci Rep, 9:7588-7588, 2019 Cited by PubMed: 31110286 DOI: 10.1038/s41598-019-44108-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.502 Å)

Structure validation