6MP1

Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with the mutant TRP1-K8 peptide

6MP1 の概要

• エントリーDOI: 10.2210/pdb6mp1/pdb
• 分子名称: TRP1-K8 peptide, Beta-2-microglobulin,H-2 class I histocompatibility antigen, D-B alpha chain, chimeric construct, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: mhc, immune system
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 50461.83

構造登録者

Clancy-Thompson, E.,Devlin, C.A.,Birnbaum, M.E.,Dougan, S.K. (登録日: 2018-10-05, 公開日: 2018-11-07, 最終更新日: 2023-10-11)

• 主引用文献: Clancy-Thompson, E.,Devlin, C.A.,Tyler, P.M.,Servos, M.M.,Ali, L.R.,Ventre, K.S.,Bhuiyan, M.A.,Bruck, P.T.,Birnbaum, M.E.,Dougan, S.K.; Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+T Cell-Effector Responses.; Cancer Immunol Res, 6:1524-1536, 2018; PubMed: 30352798; DOI: 10.1158/2326-6066.CIR-18-0348

実験手法

X-RAY DIFFRACTION (2.211 Å)