6MNS
Rhesus macaque anti-HIV V3 antibody DH753 with gp120 V3 ZAM18 peptide
Summary for 6MNS
Entry DOI | 10.2210/pdb6mns/pdb |
Descriptor | Envelope glylcoprotein, Ab DH753 heavy chain Fab fragment, Ab DH753 light chain, ... (5 entities in total) |
Functional Keywords | hiv-1 gp120 v3 antibody, immune system |
Biological source | Macaca mulatta More |
Total number of polymer chains | 6 |
Total formula weight | 99276.34 |
Authors | Nicely, N.I. (deposition date: 2018-10-02, release date: 2019-07-24, Last modification date: 2024-04-03) |
Primary citation | Han, Q.,Jones, J.A.,Nicely, N.I.,Reed, R.K.,Shen, X.,Mansouri, K.,Louder, M.,Trama, A.M.,Alam, S.M.,Edwards, R.J.,Bonsignori, M.,Tomaras, G.D.,Korber, B.,Montefiori, D.C.,Mascola, J.R.,Seaman, M.S.,Haynes, B.F.,Saunders, K.O. Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. Nat Commun, 10:2898-2898, 2019 Cited by PubMed: 31263112DOI: 10.1038/s41467-019-10899-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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